Diametric calix[6]arene-based phosphine gold(I) cavitands

Gabriele Giovanardi; Andrea Secchi; Arturo Arduini; Gianpiero Cera

doi:10.3762/bjoc.18.21

Diametric calix[6]arene-based phosphine gold(I) cavitands

Beilstein J Org Chem. 2022 Feb 10:18:190-196. doi: 10.3762/bjoc.18.21. eCollection 2022.

Authors

Gabriele Giovanardi¹, Andrea Secchi¹, Arturo Arduini¹, Gianpiero Cera¹

Affiliation

¹ Dipartimento di Scienze Chimiche, della Vita e della Sostenibilità Ambientale, Università di Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.

Abstract

We report the synthesis and characterization, in low polarity solvents, of a novel class of diametric phosphine gold(I) cavitands characterized by a 1,2,3-alternate geometry. Preliminary catalytic studies were performed on a model cycloisomerization of 1,6-enynes as a function of the relative orientation of the bonded gold(I) nuclei with respect to the macrocyclic cavity.

Keywords: 1,2,3-alternate conformation; calix[6]arenes; gold(I) catalysis; phosphines.

Grants and funding

This work was supported by the Italian MIUR (PRIN 20173L7W8 K). This work was carried out within the COMP-HUB Initiative, funded by the "Departments of Excellence" program of the Italian Ministry of Education, University and Research (MIUR, 2018–2020).