[Pityriasis rubra pilaris after COVID-19 vaccination: causal relationship or coincidence?]

Dermatologie (Heidelb). 2022 Aug;73(8):634-637. doi: 10.1007/s00105-022-04972-z. Epub 2022 Mar 16.
[Article in German]

Abstract

Numerous cutaneous side effects associated with COVID-19 vaccines have been described since their clinical approval. These include, among others, injection site reactions, urticarial, maculopapular and pityriasiform rashes or temporary exacerbations of a pre-existing chronic inflammatory skin disease. Herein we report about three cases of pityriasis rubra pilaris that occurred for the first time in close temporal relationship with the administration of a COVID-19 vaccine.

Seit der Markteinführung der COVID-19-Impfstoffe werden regelmäßig kutane Nebenwirkungen dieser Vakzine beschrieben. Diese beinhalten unter anderem lokale Impfreaktionen (insbesondere den sog. COVID-Arm), urtikarielle, makulopapulöse und pityriasiforme Exantheme oder vorübergehende Exazerbationen einer vorbestehenden chronisch entzündlichen Hauterkrankung. Wir berichten über 3 Fälle einer Pityriasis rubra pilaris, die in engem zeitlichen Zusammenhang mit der Verabreichung eines COVID-19-Impfstoffs erstmals aufgetreten sind.

Keywords: COVID-19 vaccine; Pityriasis rubra pilaris; Systemic retinoids; Vaccination reaction; mRNA vaccine.

Publication types

  • Case Reports

MeSH terms

  • COVID-19 Vaccines* / adverse effects
  • COVID-19* / prevention & control
  • Humans
  • Pityriasis Rubra Pilaris* / chemically induced
  • Skin
  • Vaccination / adverse effects

Substances

  • COVID-19 Vaccines