MAOI Antidepressants: Could They Be a Next-Generation ICB Therapy?

Front Immunol. 2022 Mar 14:13:853624. doi: 10.3389/fimmu.2022.853624. eCollection 2022.

James Brown¹, Bo Li¹, Lili Yang^{1

2

3

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¹ Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, United States.
² Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, United States.
³ Jonsson Comprehensive Cancer Center, The David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
⁴ Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, United States.

No abstract available

Keywords: T cell; immune checkpoint blockade; immunotherapy; monoamine oxidase inhibitor; nanoformulation; tumor-associated macrophage.

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