[Review of risk evaluation scores for benign end stage liver diseases recipients]

Zhonghua Wai Ke Za Zhi. 2022 Apr 1;60(4):396-400. doi: 10.3760/cma.j.cn112139-20211216-00607.
[Article in Chinese]

Abstract

Liver transplant is an unreplaceable method for benign end-stage liver disease. The risk evaluation for the waiting list recipients and for post-transplant survival could provide practical indication for organ allocation. In recent years, there are two major kinds of evaluation scores. The first kind of evaluation scores is based on model for end-stage liver disease(MELD) score,including SOFT/P-SOFT score,UCLA-FRS score and BAR score. The other evaluation system is based on the concept of acute-on-chronic liver failure,including CLIF-C-ACLF score,TAM score,AARC-ACLF score and COSSH-ACLF score. The scores based on ACLF have been shown superior power in predicting waiting list survival and post-transplant prognosis than MELD. This article reviews the two kinds of evaluation scores,aiming for the better allocation policy and the better prognosis of benign end-stage liver disease.

肝移植术是挽救终末期良性肝病患者的重要手段,评估终末期良性肝病患者等待期和移植术后生存情况可更精确地指导供器官分配。近年来提出的终末期良性肝病相关的预后评分系统可分为两大类。一类基于终末期肝病模型(MELD)评分系统,包括SOFT评分、P-SOFT评分、UCLA-FRS评分和BAR评分;另一类评分系统基于慢加急性肝功能衰竭概念,包括CLIF-C-ACLF评分、TAM评分、AARC-ACLF评分和COSSH-ACLF评分。基于慢加急性肝功能衰竭概念的评分较MELD评分在预测终末期肝病患者等待期和肝移植术后预后中展现出更优异的效能。本文总结回顾了这两类评分系统优缺点,探讨更合理的器官分配模式,以期提高终末期良性肝病患者的整体预后。.

Publication types

  • Review

MeSH terms

  • Acute-On-Chronic Liver Failure*
  • End Stage Liver Disease* / surgery
  • Humans
  • Liver Transplantation*
  • Prognosis
  • Retrospective Studies
  • Severity of Illness Index