3, 2, 1, go! Cryptosporidium counts down to sex

Aaron R Jex; Christopher J Tonkin; Stuart A Ralph

doi:10.1371/journal.pbio.3001638

3, 2, 1, go! Cryptosporidium counts down to sex

PLoS Biol. 2022 May 12;20(5):e3001638. doi: 10.1371/journal.pbio.3001638. eCollection 2022 May.

Authors

Aaron R Jex^{1

2}, Christopher J Tonkin^{3

4}, Stuart A Ralph⁵

Affiliations

¹ Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
² Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
³ Infectious Diseases and Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
⁴ Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
⁵ Department of Biochemistry and Pharmacology, Bio21 Molecular Science & Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.

Abstract

Cryptosporidium is a leading cause of death from childhood diarrhea, but its biology is poorly understood. A recent study in PLOS Biology reveals hitherto unknown aspects of the parasite's life cycle that may lead to improvements in ex vivo culture.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Cryptosporidiosis*
Cryptosporidium parvum*
Cryptosporidium* / genetics
Female
Germ Cells
Life Cycle Stages
Male

Grants and funding

A.R.J was funded through an Australian National Health and Medical Research Council Leadership grant (APP1194330). The Walter and Eliza Hall Institute of Medical Research receives support through the Victorian State Government Operational Infrastructure Support and Australian Government National Health and Medical Research Council Independent Research Institute Infrastructure Support Scheme. C.J.T. was funded through an Australian National Health and Medical Research Council ideas grant GNT1183496. S.A.R. was funded by a grant from the Australian Government National Health and Medical Research Council (APP1165354). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.