Rhodamine B derivatives-modified upconversion nanoparticles as a fluorescent turn-off-on sensor for the highly sensitive detection of Cu2+ and pyrophosphate

Zhipeng Meng; Suli Wu; Linghua Zhong; Min Zeng; Xiaoqian Sun; Lu Li; Shufen Zhang

doi:10.1039/c8ra08090a

Rhodamine B derivatives-modified upconversion nanoparticles as a fluorescent turn-off-on sensor for the highly sensitive detection of Cu²⁺ and pyrophosphate

RSC Adv. 2018 Nov 13;8(66):38075-38080. doi: 10.1039/c8ra08090a. eCollection 2018 Nov 7.

Authors

Zhipeng Meng¹, Suli Wu¹, Linghua Zhong¹, Min Zeng¹, Xiaoqian Sun¹, Lu Li², Shufen Zhang¹

Affiliations

¹ State Key Laboratory of Fine Chemicals, Dalian University of Technology 2 Linggong Road Dalian 116024 P. R. China wusuli@dlut.edu.cn.
² Qingdao University of Science and Technology, 53 Zhengzhou Road Qingdao 266000 P. R. China.

Abstract

Rhodamine B derivatives (RBP)-modified UCNPs (UCNPs@mSiO₂-RBP) were developed as a fluorescent turn-off-on sensor based on FRET and IFE to detect Cu²⁺ and pyrophosphate (PPi) with a wide linear response range (0-10 μM for Cu²⁺ and 5-35 μM for PPi, much wider than that reported previously) and high sensibility (117 nM for Cu²⁺ and 70 nM for PPi). The MTT experiments and the bioimaging experiments show its promising prospect in tissue imaging.