Two Novel Flavonoids and Cytotoxicity Evaluation from Cryptocarya yunnanensis

Chem Biodivers. 2022 Jun;19(6):e202200224. doi: 10.1002/cbdv.202200224. Epub 2022 May 13.

Abstract

Two new flavonoids, cryunchalcone (1) and cryptoyunnanone I (2), were isolated from the leaves and twigs of Cryptocarya yunnanensis. Their structures were elucidated by the detailed spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Cryunchalcone (1) is a biflavonoid constructed by a dihydrochalcone coupled with a chalcone through an unprecedented C-2''-C-6 linkage. Cryptoyunnanone I (2) is a unique complex flavanone bearing a phenylpropanoid moiety.

Keywords: Cryptocarya yunnanensis; ECD calculation; biflavonoid; complex flavanone; spectroscopic data.

MeSH terms

  • Chalcone* / chemistry
  • Cryptocarya* / chemistry
  • Flavonoids / chemistry
  • Molecular Structure
  • Plant Leaves / chemistry

Substances

  • Flavonoids
  • Chalcone