A 61-year-old woman was referred to our hospital with refractory thrombocytopenia and splenomegaly. She was diagnosed with immune thrombocytopenia 3 years prior to admission and received steroid therapy. However, her platelet count started decreasing six months prior to admission. A diagnostic and therapeutic splenectomy was performed, which led to the diagnosis of histiocytic sarcoma. The patient's platelet count recovered promptly after splenectomy, and she was in complete remission for over a year.
Keywords: Histiocytic sarcoma; Histiocytosis; Splenic neoplasms; Thrombocytopenia.
© The Author(s) under exclusive licence to The Japan Society of Clinical Oncology 2022.