Keywords: colectomy; cuffitis; inflammatory bowel disease; pouch; pouchitis; ulcerative colitis.
In this case series, 6 patients with chronic pouchitis (n = 3), cuffitis (n = 2), or Crohn’s-like disease of the pouch (n = 1) were treated with tofacitinib. One patient achieved clinical response; however, all patients ultimately discontinued therapy due to nonresponse or adverse events.