SARS-CoV-2 Mu variant emerged in Colombia in 2021 and spread globally. In 49 serum samples from vaccinees and COVID-19 survivors in Colombia, neutralization was significantly lower (p<0.0001) for Mu than a parental strain and variants of concern. Only the Omicron variant of concern demonstrated higher immune evasion.
Keywords: COVID-19; Colombia; SARS-CoV-2; acquired immunity; coronavirus disease; immune evasion; neutralization; severe acute respiratory syndrome coronavirus; vaccine efficacy; virus variants; viruses.