[Morbidity of extended pelvic lymphadenectomy during robot-assisted laparoscopic prostatectomy for localized cancer prostate]

Prog Urol. 2022 Dec;32(16):1455-1461. doi: 10.1016/j.purol.2022.07.138. Epub 2022 Sep 7.
[Article in French]

Abstract

Objectives: To assess the morbidity specific of extended pelvic lymphadenectomy during robot-assisted laparoscopic radical prostatectomy in a 8 year retrospective study.

Material: We carried out a single-center, single-surgeon retrospective study on 342 consecutive patients who underwent a robot-assisted laparoscopic radical prostatectomy and extended pelvic lymphadenectomy, from July 2010 to March 2018. Postoperative complications were recorded up to 3 months after the operation.

Results: Thirty (8.8%) patients had at least one complication related to lymphadenectomy including 1 vascular injury (0.3%), 7 injuries of the obturator nerve (2%), 5 venous thromboembolic complications (1.5%) including 4 pulmonary embolisms, 10 symptomatic lymphoceles (2.9%) and 8 lymphoedemas (2.3%). Of these complications, 13 were classified Clavien 1 (43.3%), 8 Clavien 2 (26.7%), 7 Clavien 3a (23.3%) and 2 Clavien 3b (6.7%). In univariate analysis a high age (P=0.04), high BMI (P<0.01) and pT stage (P=0.02) were significantly associated with complication whereas in multivariate analysis, only age (P=0.02) and BMI (P<0.01) lived were. In univariate analysis high BMI (P=0.04) and lymph node involvement (P=0.04) were associated with lymphatic complication. We did not find any other specific risk factor for the other complications.

Conclusion: With 8.8% of overall complications related to lymphadenectomy and 5% of complication classified Clavien grade 2 or higher, extended pelvic lymphadenectomy was not very morbid. Age and BMI were risk factors for a overall complication. BMI and lymph node involvement were risk factors for lymphatic complications.

Level of proof: 4.

Keywords: Cancer de prostate; Curage pelvien; Lymphocele; Lymphocèle; Pelvic lymphadenectomy; Prostate cancer.

Publication types

  • English Abstract

MeSH terms

  • Humans
  • Laparoscopy* / adverse effects
  • Lymph Node Excision / adverse effects
  • Lymphocele* / epidemiology
  • Lymphocele* / etiology
  • Male
  • Morbidity
  • Pelvis / pathology
  • Prostate / pathology
  • Prostatectomy / adverse effects
  • Prostatic Neoplasms* / pathology
  • Retrospective Studies
  • Robotics*