Protoboration of Alkynes and Miyaura Borylation Catalyzed by Low Loadings of Palladium

J Org Chem. 2022 Nov 4;87(21):14879-14888. doi: 10.1021/acs.joc.2c01649. Epub 2022 Oct 12.

Abstract

The versions of Miyaura borylation and protoboration of alkynes catalyzed by low loadings of palladium (400 mol ppm = 0.04 mol %) have been developed. These transformations have a broad substrate scope, good functional-group compatibility, and gram-scale synthetic ability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes*
  • Catalysis
  • Palladium*

Substances

  • Palladium
  • Alkynes