Cidofovir-induced anterior uveitis in an allogeneic stem cell transplant recipient

Transpl Infect Dis. 2022 Dec;24(6):e13974. doi: 10.1111/tid.13974. Epub 2022 Oct 28.

Abstract

Anterior uveitis is a reported complication of intravenous cidofovir, almost exclusively described in human immunodeficiency virus (HIV) infected patients treated for cytomegalovirus retinitis. In this study, we report the case of an allogeneic stem cell transplant recipient with significant visual impairment and hypotony following administration of high-dose intravenous cidofovir for hemorrhagic cystitis due to BK virus.

Keywords: BK virus; allogeneic stem cell transplant; anterior uveitis; cidofovir.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / adverse effects
  • BK Virus*
  • Cidofovir / adverse effects
  • Cystitis*
  • Cytosine / adverse effects
  • Hematopoietic Stem Cell Transplantation* / adverse effects
  • Humans
  • Organophosphonates* / adverse effects
  • Polyomavirus Infections*
  • Retrospective Studies
  • Uveitis, Anterior* / chemically induced
  • Uveitis, Anterior* / drug therapy

Substances

  • Cidofovir
  • Antiviral Agents
  • Organophosphonates
  • Cytosine