Histological Validation of FDG and PSMA-Targeted PET/CT Imaging in a Rare Tracheal Adenoid Cystic Carcinoma

Clin Nucl Med. 2023 Jan 1;48(1):e16-e18. doi: 10.1097/RLU.0000000000004441. Epub 2022 Nov 11.

Abstract

Adenoid cystic carcinomas are the second most common entity of tracheal malignancies, which have an overall incidence as low as only 0.2 in 100,000 persons per year. We present the case of a 64-year-old man with a histologically confirmed adenoid cystic carcinoma who sequentially underwent 18F-FDG PET/CT and 68Ga-PSMA-11 PET/CT within 1 day for staging 3 days before surgical resection of the tumor. Immunohistochemistry revealed PSMA expression of the tumor corroborating the PSMA PET findings.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Adenoid Cystic* / diagnostic imaging
  • Carcinoma, Adenoid Cystic* / pathology
  • Fluorodeoxyglucose F18
  • Gallium Radioisotopes
  • Humans
  • Male
  • Middle Aged
  • Positron Emission Tomography Computed Tomography / methods
  • Tracheal Neoplasms* / diagnostic imaging

Substances

  • gallium 68 PSMA-11
  • Fluorodeoxyglucose F18
  • Gallium Radioisotopes