Background: The aim of this study is to explore the relationship between reproductive variables and the prevalence of metabolic syndrome (MetS) and its components among Chinese women aged 40 years and older.
Methods: A cross-sectional study was conducted among 4453 women aged 40 years and older in Guangxi, China. The associations between women's reproductive factors and MetS were analyzed using a logistic regression model.
Results: The prevalence of MetS was 23.9% in this population. Women with MetS were mostly older, more likely to be postmenopausal, and had higher parity. Compared to women with one prior live birth, those with three or more live births had the highest odds of having MetS (odds ratio [OR] = 1.56; 95% CI, 1.23-1.99). Similarly, compared to premenopausal women, postmenopausal participants had higher odds of having MetS (OR = 1.86; 95% CI, 1.49-2.31). No associations were observed between MetS and abortion or with age at menarche.
Conclusions: Our study suggests that multiparity and menopausal status may be associated with the development of MetS. The inconsistency seen in epidemiological research to date calls for further investigation.
目的: 探讨中国40岁及以上妇女代谢综合征(MetS)患病率及其组成因素与生殖变量的关系。 方法: 对中国广西4453名40岁以上的女性进行横断面研究。使用logistic回归模型分析女性生殖影响因素与MetS之间的关系。 结果: 在该人群中, MetS的患病率为23.9%。患有MetS的女性大多年龄较大, 更有可能是绝经后, 且具有较多的胎次。与之前有1次活产的妇女相比, 那些≥3次活产的妇女发生MetS的几率最高(OR = 1.56;95%CI, 1.23-1.99)。同样, 与绝经前女性相比, 绝经后参与者发生MetS的几率更高(OR = 1.86;95% ci, 1.49-2.31)。未观察到MetS与流产或月经初潮年龄之间的关联。 结论: 我们的研究表明多胎和绝经状态可能与MetS的发展有关。迄今流行病学研究中发现的不同结果需要进一步调查。.
Keywords: menopausal; metabolic syndrome; parity; reproductive factors; 代谢综合征; 生殖影响因素; 绝经期; 胎次.
© 2022 The Authors. Journal of Diabetes published by Ruijin Hospital, Shanghai JiaoTong University School of Medicine and John Wiley & Sons Australia, Ltd.