Vaccination against influenza, measles, pertussis and varicella in workers in healthcare facilities in France: A national cross-sectional study in 2019

Sophie Vaux; Laure Fonteneau; Muriel Péfau; Anne-Gaëlle Venier; Arnaud Gautier; Sophan Soing Altrach; Pierre Parneix; Daniel Levy-Bruhl

doi:10.1016/j.vaccine.2022.12.023

Vaccination against influenza, measles, pertussis and varicella in workers in healthcare facilities in France: A national cross-sectional study in 2019

Vaccine. 2023 Jan 16;41(3):812-820. doi: 10.1016/j.vaccine.2022.12.023. Epub 2022 Dec 15.

Authors

Sophie Vaux¹, Laure Fonteneau², Muriel Péfau³, Anne-Gaëlle Venier³, Arnaud Gautier², Sophan Soing Altrach², Pierre Parneix³, Daniel Levy-Bruhl²

Affiliations

¹ Santé publique France (French Institute for Public Health Surveillance), Saint-Maurice, France. Electronic address: sophie.vaux@santepubliquefrance.fr.
² Santé publique France (French Institute for Public Health Surveillance), Saint-Maurice, France.
³ Nouvelle Aquitaine Healthcare-Associated Infection Control Centre, Bordeaux University Hospital, Bordeaux, France.

PMID: 36528442
DOI: 10.1016/j.vaccine.2022.12.023

Abstract

Background: Vaccine recommendations for healthcare workers (HCW) aim to protect them and reduce transmission to susceptible patients. We conducted a national randomised survey in 2019 whose main objectives were to estimate national vaccination coverage (VC) for measles, pertussis, varicella, and influenza in HCW working in healthcare facilities (HCF) in France, and to identify determinants associated with higher VC.

Methods: We performed a cross-sectional survey of physicians, nurses, midwives and nursing assistants in HCF using a random stratified three-stage sampling design. Data were collected during face-to-face interviews using a tablet computer and complemented with information from the individual HCW vaccination records. We investigated possible determinants of higher VC using univariate and multivariate Poisson regressions and estimated the prevalence ratio (PR).

Results: We included 8594 HCW working in 167 HCF. Self-declared VC was 73.3% (CI95%: 71.0-75.5) for measles in HCW with no history of measles (at least one dose), 53.5% (49.9-57.0) for pertussis (booster dose during adulthood), 26.4% (23.0-30.2) for varicella in HCW with no history of varicella (at least one dose) and 34.8% (32.8-37.4) for influenza. Taking into account the history of each disease and related VC, 14.6% and 10.1 % of HCW were susceptible to measles and varicella. VC varied by profession, age group, ward and sex. Higher influenza VC was observed in HCW working in wards where i) there was a staff vaccination contact person (PRa: 1.2, CI95% 1.1-1.4), ii) staff vaccination was organized in the ward (1.4: 1.2-1.6), iii) information on influenza vaccines was provided (1.2: 1.1-1.4), and iv) the ward manager supported the HCW vaccination campaign (1.3: 1.1-1.6).

Discussion: Over a 10-year period, VC for HCW working in HCF improved in France. However, vaccination objectives were not achieved for measles (95%) or influenza (80%). Vaccination efforts should be continued, especially in wards with at-risk patients.

Keywords: Healthcare workers; Influenza; Measles; Pertussis; Vaccine coverage; Varicella.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Chickenpox*
Cross-Sectional Studies
Delivery of Health Care
France / epidemiology
Health Personnel
Humans
Influenza Vaccines*
Influenza, Human* / epidemiology
Influenza, Human* / prevention & control
Measles* / prevention & control
Vaccination
Whooping Cough* / epidemiology
Whooping Cough* / prevention & control

Substances

Influenza Vaccines