We treated 35 children with different grades of vesicoureteral reflux with endoscopic injection of polytetrafluoroethylene (Teflon) behind the intravesical ureter. A total of 51 refluxing ureters was treated. In all cases absence of reflux was noted on a cystogram performed immediately after the procedure. At 3 to 12-month followup reflux was absent in 32 ureters and it recurred in 4, including 3 ureters with low grade reflux. A second injection of polytetrafluoroethylene in 3 ureters resulted in its absence, while in 1 case reimplantation was performed. The procedure is simple and reliable. An operation is avoided, hospital stay is reduced and no complications have occurred.