Activation mechanisms of clinically distinct B-Raf V600E and V600K mutants

Cancer Commun (Lond). 2023 Mar;43(3):405-408. doi: 10.1002/cac2.12395. Epub 2022 Dec 26.

Authors

Mingzhen Zhang¹, Ryan Maloney², Yonglan Liu², Hyunbum Jang¹, Ruth Nussinov^{1

3}

Affiliations

¹ Computational Structural Biology Section, Frederick National Laboratory for Cancer Research, Frederick, MD, U.S.A.
² Cancer Innovation Laboratory, National Cancer Institute, Frederick, MD, U.S.A.
³ Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Humans
Melanoma*
Proto-Oncogene Proteins B-raf
Skin Neoplasms*

Substances

Proto-Oncogene Proteins B-raf

Grants and funding

HHSN261201500003I/NH/NIH HHS/United States