Lesion or Pseudolesion? A Comprehensive Description of Perfusion-Based Liver Alterations on Contrast-Enhanced Computed Tomography and Literature Review

J Comput Assist Tomogr. 2023 Jan-Feb;47(1):9-23. doi: 10.1097/RCT.0000000000001397. Epub 2022 Dec 30.

Abstract

Pseudolesions on contrast-enhanced computed tomography represent a diagnostic challenge for radiologists because they could be difficult to distinguish from true space-occupying lesions. This article aims to provide a detailed overview of these entities based on radiological criteria (hyperattenuation or hypoattenuation, localization, morphology), as well as a brief review of the hepatic vascular anatomy and pathophysiological process. Relevant examples from hospital case series are reported as helpful hints to assist radiologists in recognizing and correctly diagnosing these abnormalities.

Publication types

  • Review

MeSH terms

  • Humans
  • Liver / diagnostic imaging
  • Liver / pathology
  • Liver Neoplasms* / diagnostic imaging
  • Liver Neoplasms* / pathology
  • Perfusion
  • Tomography, X-Ray Computed / methods