In rheumatic heart disease-associated AF, rivaroxaban increased adverse vascular outcomes vs. VKA at 3 y

Ann Intern Med. 2023 Jan;176(1):JC2. doi: 10.7326/J22-0102. Epub 2023 Jan 3.

Abstract

Connolly SJ, Karthikeyan G, Ntsekhe M, et al. Rivaroxaban in rheumatic heart disease-associated atrial fibrillation. N Engl J Med. 2022;387:978-88. 36036525.

Publication types

  • Comment

MeSH terms

  • Anticoagulants / adverse effects
  • Atrial Fibrillation* / complications
  • Atrial Fibrillation* / drug therapy
  • Factor Xa Inhibitors / adverse effects
  • Humans
  • Rheumatic Heart Disease* / chemically induced
  • Rheumatic Heart Disease* / complications
  • Rivaroxaban / adverse effects
  • Stroke* / chemically induced
  • Stroke* / prevention & control
  • Treatment Outcome
  • Vitamin K

Substances

  • Rivaroxaban
  • Anticoagulants
  • Factor Xa Inhibitors
  • Vitamin K