Antibiotic Consumption and Bacterial Resistance Rates in Hospitalized COVID-19 Patients: A Retrospective Study During the 3 First Surges

Karim Jaffal; Frédérique Bouchand; Christine Lawrence; Hélène Mascitti; Clara Duran; Djillali Annane; Aurélien Dinh

doi:10.1093/ofid/ofac680

Antibiotic Consumption and Bacterial Resistance Rates in Hospitalized COVID-19 Patients: A Retrospective Study During the 3 First Surges

Open Forum Infect Dis. 2022 Dec 16;10(1):ofac680. doi: 10.1093/ofid/ofac680. eCollection 2023 Jan.

Authors

Karim Jaffal¹, Frédérique Bouchand², Christine Lawrence³, Hélène Mascitti¹, Clara Duran¹, Djillali Annane⁴, Aurélien Dinh¹

Affiliations

¹ Infectious Disease Department, University Hospital Raymond-Poincaré, Paris Saclay University, Assistance Publique-Hôpitaux de Paris, Garches, France.
² Pharmacy, University Hospital Raymond-Poincaré, Paris Saclay University, Assistance Publique-Hôpitaux de Paris, Garches, France.
³ Microbiological Department, University Hospital Raymond-Poincaré, Paris Saclay University, Assistance Publique-Hôpitaux de Paris, Garches, France.
⁴ Intensive Care Unit, University Hospital Raymond-Poincaré, Paris Saclay University, Assistance Publique-Hôpitaux de Paris, Garches, France.

Abstract

In our hospital, during COVID-19 pandemic, overall consumption of antibiotics increased during the three first surges, mainly due to ICU prescription However, antibiotic consumption decreased in the Infectious Diseases Department. Rates of ESBL Enterobacterales remained stable.