Characterization of Trabecular Meshwork Mechanical Property Modulation After Application of Lipids

Methods Mol Biol. 2023:2625:347-351. doi: 10.1007/978-1-0716-2966-6_29.

Abstract

Treatment of lipids endogenous to the aqueous humor of the eye could serve as a potential therapy to slow the progression of glaucoma. Herein, we describe the method to treat trabecular meshwork samples in vitro with lipids and characterize changes in the samples' stiffness.

Keywords: Lipids; Stiffness; Trabecular meshwork; Young’s modulus.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aqueous Humor
  • Glaucoma*
  • Humans
  • Lipids
  • Trabecular Meshwork*

Substances

  • Lipids