Environment and the development of severe asthma in inner city population

Curr Opin Allergy Clin Immunol. 2023 Apr 1;23(2):179-184. doi: 10.1097/ACI.0000000000000890. Epub 2023 Jan 12.

Abstract

Purpose of review: Higher asthma prevalence and morbidity are seen in inner-city areas, disproportionately affecting low-income families living in substandard housing. Children within these families experience more frequent asthma exacerbations, acute care and emergency department visits, and hospitalizations, thus characterizing severe asthma. In this review, we assess recent published literature focused on indoor and outdoor exposures that contribute to the development and morbidity of asthma.

Recent findings: Many urban environmental exposures contribute to asthma burden, including tobacco/e-cigarette smoke, pest allergens, molds, and possibly synthetic chemicals such as phthalates and bisphenol A, radon, and volatile organic compounds. Individuals living in inner-city areas also experience higher levels of air pollutants and ambient heat, further perpetuating asthma incidence and severity.

Summary: This article summarizes the latest advances and provides direction for future research on risk factors, interventions, and public policy to help alleviate the burden of asthma due to urban environment exposures.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Air Pollution, Indoor* / adverse effects
  • Air Pollution, Indoor* / analysis
  • Allergens / adverse effects
  • Asthma* / epidemiology
  • Child
  • Electronic Nicotine Delivery Systems*
  • Environmental Exposure / adverse effects
  • Humans
  • Morbidity
  • Urban Population

Substances

  • Allergens