1 Intensive Care Department, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo 04024900, Brazil; Latin America Sepsis Institute, São Paulo, Brazil. Electronic address: frmachado@unifesp.br.
2 Intensive Care Department, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo 04024900, Brazil; Latin America Sepsis Institute, São Paulo, Brazil.
3 Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.