Syncope after COVID-19 Vaccination in a Young Man with Unmasking Brugada Syndrome

Intern Med. 2023 Apr 15;62(8):1191-1194. doi: 10.2169/internalmedicine.1250-22. Epub 2023 Feb 8.

Abstract

A 23-year-old man with no significant medical history was rushed to a hospital due to transient loss of consciousness with incontinence. The patient had developed a fever after his second dose of coronavirus disease 2019 (COVID-19) vaccine, and the patient was found groaning in bed approximately 40 hours after the vaccination in the early morning. The patient was diagnosed with Brugada syndrome (BrS) based on a drug-provocation test. His father had been diagnosed with BrS and died suddenly at 51 years of age. Young adults with a family history of BrS should be cautioned about fever following COVID-19 vaccination.

Keywords: electrocardiography; electrophysiological examination; fever; ventricular fibrillation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brugada Syndrome* / diagnosis
  • Brugada Syndrome* / etiology
  • COVID-19 Vaccines* / adverse effects
  • COVID-19* / prevention & control
  • Electrocardiography
  • Fever
  • Humans
  • Male
  • Syncope / etiology
  • Young Adult

Substances

  • COVID-19 Vaccines