Using a multicultural and multilingual awareness-raising strategy to enhance enrollment of racially underrepresented minoritized communities - the PassITON trial

Jasmine Bell; Sarah Cook; Terri L Edwards; Todd W Rice; Wesley H Self; Allison Wheeler; Jillian Rhoads; Thomas G Stewart; Jill M Pulley; Katelyn Benhoff; Paul A Harris; Consuelo Wilkins

doi:10.1017/cts.2022.506

Using a multicultural and multilingual awareness-raising strategy to enhance enrollment of racially underrepresented minoritized communities - the PassITON trial

J Clin Transl Sci. 2022 Dec 7;7(1):e9. doi: 10.1017/cts.2022.506. eCollection 2023.

Authors

Jasmine Bell¹, Sarah Cook¹, Terri L Edwards¹, Todd W Rice^{1

2}, Wesley H Self^{1

3}, Allison Wheeler⁴, Jillian Rhoads¹, Thomas G Stewart⁵, Jill M Pulley¹, Katelyn Benhoff⁶, Paul A Harris^{1

7}, Consuelo Wilkins^{1

8

9

10}

Affiliations

¹ Vanderbilt Institute for Clinical and Translational Research Vanderbilt University Medical Center, 2525 West End Ave, Suite 600, Nashville, TN 37203, USA.
² Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, USA.
³ Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, USA.
⁴ Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, USA.
⁵ Department of Data Science, University of Virginia, 3 Elliewood Ave, Charlottesville, VA 22903, USA.
⁶ Department of Medicine, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.
⁷ Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
⁸ Department of Medicine, Vanderbilt University Medical Center, 1161 21 Ave S, Nashville, TN 37232, USA.
⁹ Department of Internal Medicine, Meharry Medical College, 1005 Dr. D.B. Todd, Jr. Boulevard, Nashville, TN 37208 USA.
¹⁰ Office of Health Equity, Vanderbilt University Medical Center, 2525 West End Ave, Suite 600, Nashville, TN 37203, USA.

Abstract

Racially and ethnically minoritized populations have been historically excluded and underrepresented in research. This paper will describe best practices in multicultural and multilingual awareness-raising strategies used by the Recruitment Innovation Center to increase minoritized enrollment into clinical trials. The Passive Immunity Trial for Our Nation will be used as a primary example to highlight real-world application of these methods to raise awareness, engage community partners, and recruit diverse study participants.

Keywords: Recruitment; community outreach; diversity; health communication; health disparities; multicultural awareness; multilingual awareness; racial minorities; research access; retention.