Aripiprazole, brexpiprazole, and cariprazine can affect milk supply: Advice to breastfeeding mothers

Australas Psychiatry. 2023 Apr;31(2):201-204. doi: 10.1177/10398562231159510. Epub 2023 Feb 24.

Abstract

Objective: We sought to review the effects of Dopamine Receptor Partial Agonist (DRPA) antipsychotic medications on milk supply and breastfeeding.

Method: Narrative review of selected literature including animal and human data.

Results: Scant case study evidence suggests that DRPAs may lead to reduced milk supply for some.

Conclusions: Women taking DRPAs should be advised of the possibility that these may affect milk supply, and reporting should be encouraged to aid future research.

Keywords: Dopamine receptor partial agonist; breastfeeding; lactation.

Publication types

  • Review

MeSH terms

  • Animals
  • Aripiprazole / adverse effects
  • Breast Feeding*
  • Dopamine Agonists / pharmacology
  • Female
  • Humans
  • Milk*
  • Mothers

Substances

  • Aripiprazole
  • cariprazine
  • brexpiprazole
  • Dopamine Agonists