Letter to the Editors regarding "10% body weight (gain) change as criterion for the maximum tolerated dose: A critical analysis"
Regul Toxicol Pharmacol
.
2023 Mar:139:105362.
doi: 10.1016/j.yrtph.2023.105362.
Epub 2023 Feb 22.
Authors
Sir Colin L Berry
1
,
Samuel M Cohen
2
,
J Christopher Corton
3
,
Joao Lauro Viana de Camargo
4
,
Gerhard Eisenbrand
5
,
Shoji Fukushima
6
,
Helmut Greim
7
,
Klaus Weber
8
,
Ivonne M C M Rietjens
9
,
Christian Strupp
10
Affiliations
1
Queen Mary, London, UK.
2
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, USA.
3
Center for Computational Toxicology and Exposure, Office of Research and Development, Environmental Protection Agency, Durham, NC, 27711, USA.
4
State University of Sao Paulo (UNESP), SP, Brazil.
5
Department of Chemistry, Div of Food Chemistry & Toxicology, University of Kaiserslautern, Heidelberg, Germany.
6
Japan Bioassay Research Center, Hadano, Japan.
7
Technical University of Munich, Munich, Germany.
8
AnaPath GmbH, Liestal, Switzerland.
9
Division of Toxicology, Wageningen University and Research, Wageningen, the Netherlands.
10
Gowan Crop Protection Ltd., Reading, UK. Electronic address: cstrupp@gowanco.com.
PMID:
36828242
DOI:
10.1016/j.yrtph.2023.105362
No abstract available
Publication types
Letter
Comment
MeSH terms
Body Weight
Humans
Maximum Tolerated Dose
Weight Gain*