The structure of manumycin. II. Derivatives

J Antibiot (Tokyo). 1987 Nov;40(11):1541-8. doi: 10.7164/antibiotics.40.1541.

Abstract

Derivatives of manumycin (1) were obtained by acetylation and reduction, respectively, and characterized by their spectroscopic data. Structure-activity relationships of the antibiotic were discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylation
  • Alkenes / analysis
  • Anti-Bacterial Agents / analysis*
  • Chemical Phenomena
  • Chemistry
  • Hydrogenation
  • Microbial Sensitivity Tests
  • Polyenes*
  • Polyunsaturated Alkamides
  • Structure-Activity Relationship

Substances

  • Alkenes
  • Anti-Bacterial Agents
  • Polyenes
  • Polyunsaturated Alkamides
  • manumycin