Radiology-Pathology and Surgical Correlation in Astroblastoma

AJNR Am J Neuroradiol. 2023 Apr;44(4):390-395. doi: 10.3174/ajnr.A7824. Epub 2023 Mar 23.

Abstract

Astroblastoma is a rare astrocytic glial neoplasm that affects mainly young girls, peaking between 10 and 30 years of age, with low- and high-grade manifestations. Imaging characteristics are well-described, but histopathologic and, more recently, molecular analysis is fundamental to establish the diagnosis, now based on MN1 alterations. We describe a case with typical imaging and histologic features of an MN1-altered astroblastoma.

MeSH terms

  • Astrocytoma*
  • Brain Neoplasms* / diagnostic imaging
  • Brain Neoplasms* / surgery
  • Female
  • Glioma* / diagnosis
  • Humans
  • Neoplasms, Neuroepithelial* / diagnostic imaging
  • Neoplasms, Neuroepithelial* / surgery
  • Radiology*