Biofilm Formation and Control of Foodborne Pathogenic Bacteria

Molecules. 2023 Mar 7;28(6):2432. doi: 10.3390/molecules28062432.

Abstract

Biofilms are microbial aggregation membranes that are formed when microorganisms attach to the surfaces of living or nonliving things. Importantly, biofilm properties provide microorganisms with protection against environmental pressures and enhance their resistance to antimicrobial agents, contributing to microbial persistence and toxicity. Thus, bacterial biofilm formation is part of the bacterial survival mechanism. However, if foodborne pathogens form biofilms, the risk of foodborne disease infections can be greatly exacerbated, which can cause major public health risks and lead to adverse economic consequences. Therefore, research on biofilms and their removal strategies are very important in the food industry. Food waste due to spoilage within the food industry remains a global challenge to environmental sustainability and the security of food supplies. This review describes bacterial biofilm formation, elaborates on the problem associated with biofilms in the food industry, enumerates several kinds of common foodborne pathogens in biofilms, summarizes the current strategies used to eliminate or control harmful bacterial biofilm formation, introduces the current and emerging control strategies, and emphasizes future development prospects with respect to bacterial biofilms.

Keywords: biofilm; food safety; foodborne pathogens; quorum-sensing; resistance.

Publication types

  • Review

MeSH terms

  • Bacteria
  • Biofilms
  • Food
  • Food Microbiology
  • Foodborne Diseases* / microbiology
  • Foodborne Diseases* / prevention & control
  • Humans
  • Refuse Disposal*

Grants and funding

This research was funded by the National Natural Science Foundation of China (grant number 41976151).