Bilateral metachronous breast malignancies: Malignant phylloides and invasive breast carcinoma-a case report

Front Oncol. 2023 Mar 24:13:1034556. doi: 10.3389/fonc.2023.1034556. eCollection 2023.

Abstract

A 57-year-old Malay nullipara initially presented with a right breast lump that was increasing in size but defaulted follow-up. Two years later, she developed a contralateral breast lump. She only returned to the hospital when the right breast lump had become painful, 4 years from its onset. The biopsy of the right breast lump was a phylloides tumor and that of the left breast lump was a carcinoma. She had bilateral palpable axillary lymph nodes. She underwent bilateral mastectomy and axillary dissection. The pathology report confirmed the right breast lesion to be a malignant phylloides and the left breast lesion to be a carcinoma (pT3N2). She declined adjuvant treatment. A year after the surgical operation of the metachronous lesions, she had a right chest wall recurrence with widespread pulmonary metastases. She was given palliative chemotherapy but succumbed several months later.

Keywords: breast carcinoma; malignant phylloides; mastectomy; metachronous; recurrence.

Publication types

  • Case Reports

Grants and funding

The article processing fee will be funded by the Universiti Kebangsaan Malaysia Medical Centre.