Deep anterior lamellar keratoplasty (DALK) interface neovascularization: An unusual complication

J Fr Ophtalmol. 2023 Jun;46(6):611-614. doi: 10.1016/j.jfo.2022.11.018. Epub 2023 Apr 17.

Abstract

We present a case of a 31-year-old male with a past ocular history significant for keratoconus in both eyes, who underwent Deep Anterior Lamellar Keratoplasty (DALK) for his left eye and experienced graft-host interface neovascularization and interface hemorrhage as a complication. He was treated initially with removal of sutures and optimization of the ocular surface followed by subconjunctival bevacizumab, which subsequently improved his hemorrhage and neovascularization.

Keywords: Anti-VEGF; Cornea; Cornée; Deep anterior lamellar keratoplasty; Dry eye disease; Interface hemorrhage; Keratoplasty; Kératoplastie; Kératoplastie lamellaire antérieure profonde; Neovascularization; Néovascularisation; Sécheresse oculaire.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bevacizumab
  • Cornea / surgery
  • Corneal Transplantation* / adverse effects
  • Humans
  • Keratoconus* / complications
  • Keratoconus* / diagnosis
  • Keratoconus* / surgery
  • Keratoplasty, Penetrating
  • Male
  • Neovascularization, Pathologic
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Bevacizumab