Atypical Presentation of Amyloidosis in a Female Patient with Muscle Weakness

Raziyeh Lashkari; Maryam Loghman; Leila Aghaghazvini; Hiva Saffar; Bentolhoda Ziaadini; Reza Shahriarirad; Mohammad Nekooeian; Mohammad Nejadhosseinian; Majid Alikhani

doi:10.1155/2023/1553163

Atypical Presentation of Amyloidosis in a Female Patient with Muscle Weakness

Case Rep Med. 2023 Apr 13:2023:1553163. doi: 10.1155/2023/1553163. eCollection 2023.

Authors

Affiliations

¹ Semnan University of Medical Sciences, Semnan, Iran.
² Department of Internal Medicine, School of Medicine, Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
³ Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
⁴ Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
⁵ Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran.
⁶ School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
⁷ Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
⁸ Health and System Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
⁹ Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
¹⁰ Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
¹¹ Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Abstract

Muscle involvement represents a well-recognized but rare manifestation of amyloidosis. Here, we report a 40-year-old female who presented with muscle weakness, musculoskeletal pain, and proteinuria, which was eventually diagnosed as myopathic amyloidosis based on muscle biopsy results. A multidisciplinary approach appears to be the cornerstone of the diagnostic work up for recognizing the unusual amyloid myopathy.

Publication types

Case Reports