[Malignant nodular fasciitis with rare MIR22HG-USP6 fusion: report of a case]

Zhonghua Bing Li Xue Za Zhi. 2023 May 8;52(5):524-526. doi: 10.3760/cma.j.cn112151-20230131-00082.
[Article in Chinese]

Abstract

结节性筋膜炎（nodular fasciitis，NF）是一种相对常见的纤维母细胞/肌纤维母细胞性肿瘤，通常为自限性病变，复发、转移少见；有丝分裂活跃，但通常无病理性核分裂。本文报道1例具有恶性行为的NF，8年间虽经手术切除、髂内动脉化疗栓塞治疗，肿瘤仍复发并转移，显微镜下可见不典型有丝分裂，二代测序发现罕见的MIR22HG-USP6融合。.

Publication types

  • Case Reports

MeSH terms

  • Fasciitis* / genetics
  • Fasciitis* / pathology
  • Fasciitis* / surgery
  • Fibroma* / pathology
  • Gene Rearrangement
  • Humans
  • Proto-Oncogene Proteins / genetics
  • Ubiquitin Thiolesterase

Substances

  • Proto-Oncogene Proteins
  • Ubiquitin Thiolesterase
  • USP6 protein, human
  • MIRN22 microRNA, human