A case of Neurospora sitophila causing PD peritonitis

Perit Dial Int. 2023 Sep;43(5):417-420. doi: 10.1177/08968608231167242. Epub 2023 May 2.

Abstract

We describe a rare case of fungal peritoneal dialysis (PD) peritonitis caused by the ascomycete fungus Neurospora sitophila (N. sitophila). The patient had little response to initial antibiotics and PD catheter removal was necessary for source control. The fungal biomarker β-d-glucan (BDG) was positive prior to N. sitophila being cultured and remained positive for 6 months after discharge. Use of BDG early in the assessment of PD peritonitis may reduce time to definitive therapy in fungal peritonitis.

Keywords: PD peritonitis; fungal biomarkers; fungal infection; fungal peritonitis; peritoneal dialysis; β-D-glucan.

Publication types

  • Case Reports

MeSH terms

  • Biomarkers
  • Humans
  • Mycoses*
  • Neurospora*
  • Peritoneal Dialysis* / adverse effects
  • Peritonitis* / diagnosis
  • Peritonitis* / drug therapy
  • Peritonitis* / etiology
  • Tolnaftate

Substances

  • Biomarkers
  • Tolnaftate

Supplementary concepts

  • Neurospora sitophila