Combining general and central measures of adiposity to identify risk of hypertension: a cross-sectional survey in rural India

Obes Res Clin Pract. 2023 May-Jun;17(3):249-256. doi: 10.1016/j.orcp.2023.04.005. Epub 2023 May 2.

Abstract

Aim: In three socioeconomically diverse regions of rural India, we determined the optimal cut-offs for definition of overweight, the prevalence of overweight, and the relationships between measures of overweight and risk of hypertension.

Subjects and methods: Villages were randomly sampled within rural Trivandrum, West Godavari, and Rishi Valley. Sampling of individuals was stratified by age group and sex. Cut-offs for measures of adiposity were compared using area under the receiver operating characteristic curve. Associations between hypertension and definitions of overweight were assessed by logistic regression.

Results: Of 11 657 participants (50 % male; median age 45 years), 29.8 % had hypertension. Large proportions were overweight as defined by body mass index (BMI) ≥ 23 kg/m2 (47.7 %), waist circumference (WC) ≥ 90 cm for men or ≥ 80 cm for women (39.6 %), waist-hip ratio (WHR) ≥ 0.9 for men or ≥ 0.8 for women (65.6 %), waist-height ratio (WHtR) ≥ 0.5 (62.5 %), or by BMI plus either WHR, WC or WHtR (45.0 %). All definitions of overweight were associated with hypertension, with optimal cut-offs being at, or close to, the World Health Organization (WHO) Asia-Pacific standards. Having overweight according to both BMI and a measure of central adiposity was associated with approximately twice the risk of hypertension than overweight defined by only one measure.

Conclusions: Overweight, as assessed by both general and central measures, is prevalent in rural southern India. WHO standard cut-offs are appropriate in this setting for assessing risk of hypertension. However, combining BMI with a measure of central adiposity identifies risk of hypertension better than any single measure. The risk of hypertension is significantly greater in those centrally and generally overweight than those overweight by a single measure.

Keywords: Body mass index; Hypertension; India; Prevalence; Waist-hip ratio.

MeSH terms

  • Adiposity*
  • Body Mass Index
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypertension* / diagnosis
  • Hypertension* / epidemiology
  • Hypertension* / etiology
  • India / epidemiology
  • Male
  • Middle Aged
  • Obesity / epidemiology
  • Obesity, Abdominal / complications
  • Obesity, Abdominal / epidemiology
  • Overweight / complications
  • Overweight / epidemiology
  • ROC Curve
  • Risk Factors
  • Waist Circumference
  • Waist-Hip Ratio