Macrophages show up in style when Th2 lymphocytes organize their homecoming

Xin Li; Claudia V Jakubzick

doi:10.1016/j.immuni.2023.04.007

Macrophages show up in style when Th2 lymphocytes organize their homecoming

Immunity. 2023 May 9;56(5):900-902. doi: 10.1016/j.immuni.2023.04.007.

Authors

Xin Li¹, Claudia V Jakubzick²

Affiliations

¹ Department of Microbiology and Immunology, Dartmouth Geisel School of Medicine, Hanover, NH 03756, USA.
² Department of Microbiology and Immunology, Dartmouth Geisel School of Medicine, Hanover, NH 03756, USA. Electronic address: claudia.jakubzick@dartmouth.edu.

Abstract

Monocytes can differentiate into tissue-resident pleural macrophages, but the mechanisms underlying this process are not yet fully understood. In this issue of Immunity, Finlay et al.¹ show that Th2 cytokines promote this differentiation in resistant mice infected with Litomosoides sigmodontis.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Animals
Cytokines
Filariasis*
Filarioidea*
Lymphocytes
Macrophages
Mice
Mice, Inbred BALB C

Substances

Cytokines

Grants and funding

R35 HL155458/HL/NHLBI NIH HHS/United States