Gender-Based Frailty in Multiple Orthopedic Fractures

Am Surg. 2023 Sep;89(9):3924-3927. doi: 10.1177/00031348231173967. Epub 2023 May 24.

Abstract

The 5-factor modified frailty index (mFI-5) has been used as a prognostic tool to identify patients at higher risk for complications and mortality but has not been used to assess the relationship between frailty and extent of injury following ground-level falls. The aim of this study was to determine if mFI-5 is associated with increased risk for combined femur-humerus fractures compared to isolated femur fractures in geriatric patients. A retrospective analysis of 2017-2018 American College of Surgeons Trauma Quality Improvement Program (ACS-TQIP) data identified 190 836 patients with femur fractures and 5054 patients with combined femur-humerus fractures. In multivariate analysis, gender was the only statistically significant predictor for risk of combined vs isolated fractures (OR 1.69, 95% CI [1.65, 1.74], P < .001). While outcome data for the mFI-5 repeatedly shows increased risk for adverse events, this tool may over-estimate the disease specific risk factors rather than the overall frailty state of the patient and diminish its predictive power.

Keywords: fractures; frailty; geriatrics; ground-level falls; trauma.

MeSH terms

  • Aged
  • Femoral Fractures* / complications
  • Fractures, Multiple* / complications
  • Frailty* / complications
  • Frailty* / epidemiology
  • Humans
  • Humeral Fractures* / complications
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors