Safety and Efficacy Associated With a Family-Centered Procedural Sedation Protocol for Children With Autism Spectrum Disorder or Developmental Delay

Cyril Sahyoun; Baruch Krauss; Martina Bevacqua; Artiom Antonsen; Laurent Jardinier; Egidio Barbi

doi:10.1001/jamanetworkopen.2023.15974

Safety and Efficacy Associated With a Family-Centered Procedural Sedation Protocol for Children With Autism Spectrum Disorder or Developmental Delay

JAMA Netw Open. 2023 May 1;6(5):e2315974. doi: 10.1001/jamanetworkopen.2023.15974.

Authors

Cyril Sahyoun¹, Baruch Krauss², Martina Bevacqua¹, Artiom Antonsen³, Laurent Jardinier³, Egidio Barbi^{4

5}

Affiliations

¹ Division of Pediatric Emergency Medicine, Children's Hospital of Geneva, Geneva University Hospitals, Geneva, Switzerland.
² Division of Emergency Medicine, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
³ Divisions of General Pediatrics and Pediatric Subspecialties, Children's Hospital of Geneva, Geneva University Hospitals, Geneva, Switzerland.
⁴ Department of Pediatrics, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
⁵ University of Trieste, Trieste, Italy.

No abstract available

Plain language summary

This case series describes a family-centered procedural sedation protocol including home desensitization to intranasal drug delivery, environmental modification, and intranasal dexmedetomidine combined with nitrous oxide for children with autism spectrum disorder or developmental delay.

MeSH terms

Anesthesia*
Autism Spectrum Disorder*
Child
Dexmedetomidine*
Humans
Hypnotics and Sedatives / therapeutic use

Substances

Hypnotics and Sedatives
Dexmedetomidine