A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule

Alpa Kanji; James Carton; Caroline Hewitt; Derrick Phillips

doi:10.7759/cureus.39231

A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule

Cureus. 2023 May 19;15(5):e39231. doi: 10.7759/cureus.39231. eCollection 2023 May.

Authors

Alpa Kanji¹, James Carton², Caroline Hewitt¹, Derrick Phillips¹

Affiliations

¹ Dermatology, Imperial College Healthcare NHS (National Health Service) Trust, London, GBR.
² Histopathology, Imperial College Healthcare NHS (National Health Service) Trust, London, GBR.

Abstract

CD34-positive dermal fibromas (PDFs) are cutaneous neoplasms that display a characteristic pattern of superficial dermal spindle cell proliferation on histopathology evaluation. They are clinically heterogenous in presentation and thought to follow a benign course. CD34-PDFs have features that overlap with dermatofibrosarcoma protuberans (DFSP), a locally aggressive low-grade superficial sarcoma. Cytogenetic studies are essential to distinguish the two. This report presents the case of a 38-year-old female with a CD34-PDF on the right antecubital fossa.

Keywords: benign lesions; cytogenetic studies; dermatofibrosarcoma protruberans; fibroma; spindle cell.

Publication types

Case Reports