Berberine for Adjunct/Alternative Treatment of Dyslipidemia: A Literature Review

Cureus. 2023 May 20;15(5):e39261. doi: 10.7759/cureus.39261. eCollection 2023 May.

Abstract

Berberine (BBR) is an ancient plant popular in China and is used to treat dyslipidemia, among other cardiovascular and metabolic-related diseases. BBR has historically been regarded as having multiple benefits, with a few clinical trials indicating this fact. We searched PubMed, Embase, and Google Scholar with the following keywords: Berberidaceae, berberine, Berberis spp., dyslipidemia, atherosclerosis, and inflammation. We synthesized the information within the literature to provide an updated review of BBR, its potential, and its applicability in real-world medicine in the future. This review sought to evaluate the literature and advancement in BBR's efficacy regarding dyslipidemia, inflammation, and atherosclerosis.

Keywords: atherosclerosis; berberidaceae; berberine; berberis spp; dyslipidemia; inflammation.

Publication types

  • Review