Autoimmune hepatitis complicated by adult-onset Still's disease during treatment with tocilizumab: A case report from acute onset to recurrence

Daiki Uchihara; Tomohiro Suzuki; Yudai Koya; Mayumi Tai; Osamu Ichii; Nobuo Matsuhashi; Yutaka Ejiri; Tomoya Kato; Yuichi Honma; Michihiko Shibata; Masaru Harada

doi:10.1002/ccr3.7530

Autoimmune hepatitis complicated by adult-onset Still's disease during treatment with tocilizumab: A case report from acute onset to recurrence

Clin Case Rep. 2023 Jun 29;11(7):e7530. doi: 10.1002/ccr3.7530. eCollection 2023 Jul.

Authors

Daiki Uchihara^{1

2}, Tomohiro Suzuki¹, Yudai Koya², Mayumi Tai^{1

2}, Osamu Ichii¹, Nobuo Matsuhashi¹, Yutaka Ejiri¹, Tomoya Kato³, Yuichi Honma², Michihiko Shibata², Masaru Harada²

Affiliations

¹ Department of Gastroenterology Fukushima Rosai Hospital Iwaki Japan.
² Third Department of Internal Medicine, School of Medicine University of Occupational and Environmental Health Kitakyushu Japan.
³ Department of Pathology Fukushima Rosai Hospital Iwaki Japan.

Abstract

The characteristics of liver dysfunction due to adult-onset Still's disease are not specific. Differentiating from autoimmune hepatitis is important in deciding whether to continue corticosteroid therapy, and also in terms of management of cirrhosis and surveillance of hepatocellular carcinoma. Liver biopsy is thought to be the most important determinant for differential diagnosis.

Keywords: adult‐onset Still's disease; autoimmune hepatitis; liver biopsy.

Publication types

Case Reports