State-of-the-Art: Noninvasive Assessment of Left Ventricular Function Through Myocardial Work

Ana Moya; Dimitri Buytaert; Martin Penicka; Jozef Bartunek; Marc Vanderheyden

doi:10.1016/j.echo.2023.07.002

State-of-the-Art: Noninvasive Assessment of Left Ventricular Function Through Myocardial Work

J Am Soc Echocardiogr. 2023 Oct;36(10):1027-1042. doi: 10.1016/j.echo.2023.07.002. Epub 2023 Jul 10.

Authors

Ana Moya¹, Dimitri Buytaert², Martin Penicka², Jozef Bartunek², Marc Vanderheyden²

Affiliations

¹ Cardiovascular Center and Cardiovascular Research Centre, OLV Hospital, Aalst, Belgium; CardioPath PhD Program, Department of Advanced Biomedical Sciences, Cardiovascular Pathophysiology and Therapeutics, University of Naples Federico II, Naples, Italy. Electronic address: ana.moya@olvz-aalst.be.
² Cardiovascular Center and Cardiovascular Research Centre, OLV Hospital, Aalst, Belgium.

PMID: 37437670
DOI: 10.1016/j.echo.2023.07.002

Abstract

The assessment of myocardial work (MW) using noninvasive pressure-strain loop analysis is a novel echocardiographic method that provides a more precise assessment of cardiac performance by considering the left ventricular loading condition. By integrating various MW components such as index, efficiency, and constructive and wasted work, an extensive analysis of left ventricular mechanics and energetics can be achieved. This approach offers a more comprehensive assessment of global cardiac function and performance, surpassing conventional surrogate indices. In this review, we aim to summarize the existing knowledge on MW and its distinctive characteristics in various cardiac pathologies.

Keywords: Afterload; Heart failure; Myocardial dysfunction; Myocardial work; Pressure-strain loops; Strain.

Publication types

Review