In vivo treatment of tyrosinaemia with hypercompact Cas12f1

Cell Discov. 2023 Jul 18;9(1):73. doi: 10.1038/s41421-023-00554-y.

Ruochen Guo^#^{1

2}, Zhifang Li^#^{1

3}, Guoling Li^#², Hainan Zhang^#⁴, Chang Zhang^#², Xiaona Huo^{1

3}, Xiaoyin Zhang^{1

3}, Xiali Yang², Rongrong Yang^{1

3}, Yuanhua Liu², Xiaozhi Sun^{1

5}, Xinyu Liu², Hui Yang^{6

7

8}, Yingsi Zhou⁹, Chunlong Xu^{10

11

12}

¹ Lingang Laboratory, Shanghai, China.
² Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
³ Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China.
⁴ HuidaGene Therapeutics Inc, Shanghai, China.
⁵ School of Life Sciences and Technology, ShanghaiTech University, Shanghai, China.
⁶ Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China. huiyang@huidagene.com.
⁷ Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China. huiyang@huidagene.com.
⁸ HuidaGene Therapeutics Inc, Shanghai, China. huiyang@huidagene.com.
⁹ HuidaGene Therapeutics Inc, Shanghai, China. yingsizhou@huidagene.com.
¹⁰ Lingang Laboratory, Shanghai, China. xucl@lglab.ac.cn.
¹¹ Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China. xucl@lglab.ac.cn.
¹² School of Life Sciences and Technology, ShanghaiTech University, Shanghai, China. xucl@lglab.ac.cn.

^# Contributed equally.

No abstract available

Publication types