Spectrometric Assessment of Generic and Brand Drug Quality for a Sentinel Screening Network

Appl Spectrosc. 2023 Aug;77(8):915-927. doi: 10.1177/00037028231184478. Epub 2023 Jul 20.

Abstract

The U.S. Food and Drug Administration (FDA) is a worldwide leader among analogous regulatory organizations in other countries. The FDA uses current good manufacturing practices to regulate the processes that produce drugs. Nevertheless, investigative journalists have pointed out problems in the drug supply, and pharmacies are not required to test the drugs they receive. The University of Kentucky Drug Quality Study does perform screening on the sterile injectable drugs that it receives and regularly reports new findings to FDA, practitioners, and the public. A Sentinel Screening Network of academic health systems could provide independent data on drug quality to FDA not available through manufacturers.

Keywords: NIR spectrometery; Near-infrared spectrometry; Raman spectrometry; sterile pharmaceuticals.

MeSH terms

  • Drugs, Generic*
  • Pharmaceutical Preparations
  • United States
  • United States Food and Drug Administration

Substances

  • Drugs, Generic
  • Pharmaceutical Preparations