Displacement of Submacular Hemorrhage With Vitrectomy Combined With Subretinal Balanced Salt Solution and Air

Retina. 2023 Dec 1;43(12):2194-2198. doi: 10.1097/IAE.0000000000003879.

Abstract

Purpose: To describe a technique of displacement of submacular hemorrhage (SMH) using subretinal injection of balanced salt solution and filtered air.

Methods: Patients presenting within 2 weeks of massive SMH (>4 disk diameter) were prospectively included. All patients underwent 25-gauge pars plana vitrectomy, posterior vitreous detachment, injection of subretinal balanced salt solution and filtered air followed by partial fluid air exchange, 20% sulfur hexafluoride tamponade, and heads-up positioning postoperatively. Degree of displacement of SMH was assessed at 1 month and change in best-corrected visual acuity was assessed at 3 months.

Results: Ten patients with massive SMH who underwent the aforementioned procedure were included. Complete displacement of bleed from the macula was achieved in nine (90%) of 10 eyes at 1 month. There was significant improvement in best-corrected visual acuity from baseline at 1 month ( P = 0.015) and 3 months ( P = 0.043).

Conclusion: Pars plana vitrectomy with injection of subretinal balanced salt solution and filtered air was well-tolerated and efficacious in displacing large and thick SMH in patients operated within 2 weeks of onset of symptoms.

MeSH terms

  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Injections, Intraocular
  • Macula Lutea*
  • Retinal Hemorrhage / diagnosis
  • Retinal Hemorrhage / surgery
  • Retrospective Studies
  • Tissue Plasminogen Activator*
  • Treatment Outcome
  • Vitrectomy / methods

Substances

  • Tissue Plasminogen Activator
  • Fibrinolytic Agents