Current Status of Diagnosis and Treatment of Colorectal Cancer in Asian Countries: A Questionnaire Survey

Digestion. 2024;105(1):62-68. doi: 10.1159/000531706. Epub 2023 Jul 27.

Abstract

Introduction: Diagnostic and therapeutic methods for colorectal cancer (CRC) have advanced; however, they may be inaccessible worldwide, and their widespread use is challenging. This questionnaire survey investigates the current status of diagnosis and treatment of early-stage CRC in Asian countries.

Methods: Responses to the questionnaire were obtained from 213 doctors at different institutions in 8 countries and regions. The questionnaire consisted of 39 questions on the following four topics: noninvasive diagnosis other than endoscopy (6 questions), diagnosis by magnification and image-enhanced endoscopy (IEE) including artificial intelligence (AI) (10 questions), endoscopic submucosal dissection (ESD), proper use among other therapeutic methods (11 questions), and pathologic diagnosis and surveillance (12 questions).

Results: Although 101 of 213 respondents were affiliated with academic hospitals, there were disparities among countries and regions in the dissemination of advanced technologies, such as IEE, AI, and ESD. The NICE classification is widely used for the diagnosis of colorectal tumors using IEE, while the JNET classification with magnification was used in countries such as Japan (65/70, 92.9%) and China (16/22, 72.7%). Of the 211 respondents, 208 (98.6%) assumed that en bloc resection should be achieved for carcinomas, and 180 of 212 (84.9%) believed that ESD was the most suitable in cases with a diameter larger than 2 cm. However, colorectal ESD is not widespread in countries such as Thailand, the Philippines, and Indonesia.

Conclusion: The promotion of advanced technologies and education should be continual to enable more people to benefit from them.

Keywords: Colonoscopy; Colorectal cancer; Colorectal tumor; en bloc resection.

MeSH terms

  • Artificial Intelligence
  • Colonoscopy
  • Colorectal Neoplasms* / diagnosis
  • Colorectal Neoplasms* / surgery
  • Dissection / methods
  • Endoscopic Mucosal Resection* / methods
  • Endoscopy, Gastrointestinal / methods
  • Humans
  • Intestinal Mucosa / pathology
  • Retrospective Studies
  • Surveys and Questionnaires
  • Treatment Outcome