Fat emboli-Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember-Case series

Respirol Case Rep. 2023 Sep 8;11(10):e01214. doi: 10.1002/rcr2.1214. eCollection 2023 Oct.

Abstract

Fat embolism syndrome (FES) is a rare but potentially fatal complication of trauma or orthopaedic surgery, which presents predominantly with pulmonary symptoms. The rapid worsening respiratory failure in a previously normal orthopaedic surgery or trauma patients usually get evaluated for pulmonary embolism, fat-embolism-related acute respiratory distress or transfusion related acute lung injury. Orthopaedic surgeons and clinicians need to be aware of related entity termed 'Fat Embolism related Diffuse Alveolar Haemorrhage' (FEDAH). The clinical presentation in an orthopaedic surgery of trauma patient with FEDAH are haemoptysis, worsening type 1 respiratory failure and oxygen requirement, drop in haemoglobin levels with chest x-ray/computed tomography suggestive of Diffuse alveolar haemorrhage (DAH). Early bronchoscopy and bronchoalveolar lavage (BAL) confirmation of DAH, presence of BAL haemosiderophages and lipid-laden macrophages are the pointers in the early diagnosis of FEDAH. It needs a high clinical suspicion and interdepartmental collaborative measures. Timely referral from orthopaedic surgeons, early bronchoscopy and treatment with steroids is key in diagnosis and management.

Keywords: Bronchoalveolar lavage (BAL); diffuse alveolar haemorrhage (DAH); fat embolism related diffuse alveolar haemorrhage (FEDAH); fat embolism syndrome (FES).

Publication types

  • Case Reports