Glycopyrrolate-induced polyuria: An unexpected side effect

J Neurosci Rural Pract. 2023 Jul-Sep;14(3):525-527. doi: 10.25259/JNRP_73_2023. Epub 2023 Jun 5.

Abstract

Polyuria is urine output exceeding 3 L/d in adults, primarily due to solute and water diuresis. In a hospital setting, mannitol and diuretics commonly lead to polyuria. We have found an interesting association of polyuria with glycopyrrolate; to the best of our knowledge, no case is reported in the literature. Here, we are describing a case of Guillain-Barre Syndrome, which developed polyuria during the hospital stay, which was secondary to glycopyrrolate.

Keywords: Glycopyrrolate; Guillain–barre syndrome; Polyuria.

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  • Case Reports

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